The Core Histone N-Terminal Tail Domains Negatively Regulate Binding of Transcription Factor IIIA to a Nucleosome Containing a 5S RNA Gene via a Novel Mechanism

Reconstitution of a DNA fragment containing a 5S RNA gene from Xenopus borealis into a nucleosome greatly restricts binding of the primary 5S transcription factor, TFIIIA. Consistent with transcription experiments using reconstituted templates, removal of the histone tail domains stimulates TFIIIA b...

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Detalhes bibliográficos
Main Authors: Yang, Zungyoon, Zheng, Chunyang, Thiriet, Christophe, Hayes, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538782/
https://ncbi.nlm.nih.gov/pubmed/15601846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.1.241-249.2005
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