Impact of CFTR Modulation on Intestinal pH, Motility, and Clinical Outcomes in Patients With Cystic Fibrosis and the G551D Mutation

OBJECTIVES: A defect in bicarbonate secretion contributes to the pathophysiology of gastrointestinal complications in patients with cystic fibrosis (CF). We measured gastrointestinal pH, clinical outcomes, and intestinal transit profiles in patients with the G551D mutation before and after treatment...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Transl Gastroenterol
Egile Nagusiak: Gelfond, Daniel, Heltshe, Sonya, Ma, Changxing, Rowe, Steven M, Frederick, Carla, Uluer, Ahmet, Sicilian, Leonard, Konstan, Michael, Tullis, Elizabeth, Roach, R N Christine, Griffin, Katherine, Joseloff, Elizabeth, Borowitz, Drucy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Original Contributions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387753/
https://ncbi.nlm.nih.gov/pubmed/28300821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2017.10
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