Molecular Mechanism of hTid-1, the Human Homolog of Drosophila Tumor Suppressor l(2)Tid, in the Regulation of NF-κB Activity and Suppression of Tumor Growth

hTid-1, a human homolog of the Drosophila tumor suppressor l(2)Tid and a novel DnaJ protein, regulates the activity of nuclear factor κB (NF-κB), but its mechanism is not established. We report here that hTid-1 strongly associated with the cytoplasmic protein complex of NF-κB-IκB through direct inte...

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Hlavní autoři: Cheng, Hua, Cenciarelli, Carlo, Nelkin, Gina, Tsan, Rachel, Fan, Dominic, Cheng-Mayer, Cecilia, Fidler, Isaiah J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC538758/
https://ncbi.nlm.nih.gov/pubmed/15601829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.1.44-59.2005
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