Systemic Priming-Boosting Immunization with a Trivalent Plasmid DNA and Inactivated Murine Cytomegalovirus (MCMV) Vaccine Provides Long-Term Protection against Viral Replication following Systemic or Mucosal MCMV Challenge

We previously demonstrated that vaccination of BALB/c mice with a pool of 13 plasmid DNAs (pDNAs) expressing murine cytomegalovirus (MCMV) genes followed by formalin-inactivated MCMV (FI-MCMV) resulted in complete protection against viral replication in the spleen and salivary glands following suble...

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Pubblicato in:	J Virol
Autori principali:	Morello, Christopher S., Ye, Ming, Hung, Stephanie, Kelley, Laura A., Spector, Deborah H.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2005
Soggetti:	Vaccines and Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538742/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15596812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.1.159-175.2005
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