Dose-dependent artificial prolongation of prothrombin time by interaction between daptomycin and test reagents in patients receiving warfarin: a prospective in vivo clinical study

BACKGROUND: Daptomycin has been reported to cause artificial prolongation of prothrombin time (PT) by interacting with some test reagents of PT. This prolongation was particularly prominent with high concentrations of daptomycin in vitro. However, whether this prolongation is important in clinical s...

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Detalhes bibliográficos
Publicado no:Ann Clin Microbiol Antimicrob
Main Authors: Saito, Makoto, Hatakeyama, Shuji, Hashimoto, Hideki, Suzuki, Takumitsu, Jubishi, Daisuke, Kaneko, Makoto, Kume, Yukio, Yamamoto, Takehito, Suzuki, Hiroshi, Yotsuyanagi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387382/
https://ncbi.nlm.nih.gov/pubmed/28399872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12941-017-0203-3
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