Herpes Simplex Virus Type 1 gK Is Required for gB-Mediated Virus-Induced Cell Fusion, While neither gB and gK nor gB and UL20p Function Redundantly in Virion De-Envelopment

Multiple amino acid changes within herpes simplex virus type 1 (HSV-1) gB and gK cause extensive virus-induced cell fusion and the formation of multinucleated cells (syncytia). Early reports established that syncytial mutations in gK could not cause cell-to-cell fusion in the absence of gB. To inves...

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發表在:J Virol
Main Authors: Melancon, Jeffrey M., Luna, Rafael E., Foster, Timothy P., Kousoulas, Konstantin G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2005
主題:
Structure and Assembly
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538735/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15596825/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.1.299-313.2005
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