Substitution of Feline Leukemia Virus Long Terminal Repeat Sequences into Murine Leukemia Virus Alters the Pattern of Insertional Activation and Identifies New Common Insertion Sites

The recombinant retrovirus, MoFe2-MuLV (MoFe2), was constructed by replacing the U3 region of Moloney murine leukemia virus (M-MuLV) with homologous sequences from the FeLV-945 LTR. NIH/Swiss mice neonatally inoculated with MoFe2 developed T-cell lymphomas of immature thymocyte surface phenotype. Mo...

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Autores principales: Johnson, Chassidy, Lobelle-Rich, Patricia A., Puetter, Adriane, Levy, Laura S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC538733/
https://ncbi.nlm.nih.gov/pubmed/15596801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.1.57-66.2005
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