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Itraconazole induces apoptosis and cell cycle arrest via inhibiting Hedgehog signaling in gastric cancer cells

BACKGROUND: Itraconazole has been proved therapeutically effective against a variety of human cancers. This study assessed the effect of itraconazole on the Hedgehog (Hh) pathway and proliferation of human gastric cancer cells. METHODS: CCK-8 assay and colony formation assay were used to assess the...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Hu, Qiang, Hou, Yi-Chao, Huang, Jiao, Fang, Jing-Yuan, Xiong, Hua
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387201/
https://ncbi.nlm.nih.gov/pubmed/28399898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0526-0
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