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Crystal Structure of Complete Rhinovirus RNA Polymerase Suggests Front Loading of Protein Primer

Picornaviruses utilize virally encoded RNA polymerase and a uridylylated protein primer to ensure replication of the entire viral genome. The molecular details of this mechanism are not well understood due to the lack of structural information. We report the crystal structure of human rhinovirus 16...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Appleby, Todd C., Luecke, Hartmut, Shim, Jae Hoon, Wu, Jim Z., Cheney, I. Wayne, Zhong, Weidong, Vogeley, Lutz, Hong, Zhi, Yao, Nanhua
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2005
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538717/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15596823/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.1.277-288.2005
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