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Sildenafil attenuates hypoxic pulmonary remodelling by inhibiting bone marrow progenitor cells

The recruitment of bone marrow (BM)‐derived progenitor cells to the lung is related to pulmonary remodelling and the pathogenesis of pulmonary hypertension (PH). Although sildenafil is a known target in PH treatment, the underlying molecular mechanism is still elusive. To test the hypothesis that th...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cell Mol Med
Päätekijät: Favre, Shirley, Gambini, Elisa, Nigro, Patrizia, Scopece, Alessandro, Bianciardi, Paola, Caretti, Anna, Pompilio, Giulio, Corno, Antonio F., Vassalli, Giuseppe, von Segesser, Ludwig K., Samaja, Michele, Milano, Giuseppina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387166/
https://ncbi.nlm.nih.gov/pubmed/27860185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13026
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