Sildenafil attenuates hypoxic pulmonary remodelling by inhibiting bone marrow progenitor cells

The recruitment of bone marrow (BM)‐derived progenitor cells to the lung is related to pulmonary remodelling and the pathogenesis of pulmonary hypertension (PH). Although sildenafil is a known target in PH treatment, the underlying molecular mechanism is still elusive. To test the hypothesis that th...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Favre, Shirley, Gambini, Elisa, Nigro, Patrizia, Scopece, Alessandro, Bianciardi, Paola, Caretti, Anna, Pompilio, Giulio, Corno, Antonio F., Vassalli, Giuseppe, von Segesser, Ludwig K., Samaja, Michele, Milano, Giuseppina
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387166/
https://ncbi.nlm.nih.gov/pubmed/27860185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13026
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