Sildenafil attenuates hypoxic pulmonary remodelling by inhibiting bone marrow progenitor cells

The recruitment of bone marrow (BM)‐derived progenitor cells to the lung is related to pulmonary remodelling and the pathogenesis of pulmonary hypertension (PH). Although sildenafil is a known target in PH treatment, the underlying molecular mechanism is still elusive. To test the hypothesis that th...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Favre, Shirley, Gambini, Elisa, Nigro, Patrizia, Scopece, Alessandro, Bianciardi, Paola, Caretti, Anna, Pompilio, Giulio, Corno, Antonio F., Vassalli, Giuseppe, von Segesser, Ludwig K., Samaja, Michele, Milano, Giuseppina
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387166/
https://ncbi.nlm.nih.gov/pubmed/27860185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13026
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