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Cyclophilin Interactions with Incoming Human Immunodeficiency Virus Type 1 Capsids with Opposing Effects on Infectivity in Human Cells

Cyclophilin A (CypA) is a peptidyl-prolyl isomerase that binds to the capsid protein (CA) of human immunodeficiency virus type 1 (HIV-1) and by doing so facilitates HIV-1 replication. Although CypA is incorporated into HIV-1 virions by virtue of CypA-Gag interactions that occur during virion assembl...

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Bibliografiske detaljer
Main Authors: Hatziioannou, Theodora, Perez-Caballero, David, Cowan, Simone, Bieniasz, Paul D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538701/
https://ncbi.nlm.nih.gov/pubmed/15596813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.1.176-183.2005
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