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Hepatitis C Virus Nonstructural 5A Protein (HCV-NS5A) Inhibits Hepatocyte Apoptosis through the NF-κb/miR-503/bcl-2 Pathway

The nonstructural protein 5A (NS5A) encoded by the human hepatitis C virus (HCV) RNA genome is a multifunctional phosphoprotein. To analyse the influence of NS5A on apoptosis, we established an Hep-NS5A cell line (HepG2 cells that stably express NS5A) and induced apoptosis using tumour necrosis fact...

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Detalhes bibliográficos
Publicado no:Mol Cells
Main Authors: Xie, Zhengyuan, Xiao, Zhihua, Wang, Fenfen
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Molecular and Cellular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386958/
https://ncbi.nlm.nih.gov/pubmed/28343379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2017.2299
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