The Infectivity and Lytic Activity of Minute Virus of Mice Wild-Type and Derived Vector Particles Are Strikingly Different

Gene therapy vectors have been developed from autonomous rodent parvoviruses that carry a therapeutic gene or a marker gene in place of the genes encoding the capsid proteins. These vectors are currently evaluated in preclinical experiments. The infectivity of the vector particles deriving from the...

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Autori principali: Lang, Susanne I., Boelz, Stephanie, Stroh-Dege, Alexandra Y., Rommelaere, Jean, Dinsart, Christiane, Cornelis, Jan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Gene Therapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC538690/
https://ncbi.nlm.nih.gov/pubmed/15596824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.1.289-298.2005
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