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Time-Variant Genetic Effects as a Cause for Preterm Birth: Insights from a Population of Maternal Cousins in Sweden

Preterm delivery (PTD) is the leading cause of neonatal mortality worldwide, yet its etiology remains largely unexplained. We propose that the genetic factors controlling this trait could act in a nonuniform manner during pregnancy, with each factor having a unique “window of sensitivity.” We test t...

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Podrobná bibliografie
Vydáno v:G3 (Bethesda)
Hlavní autoři: Juodakis, Julius, Bacelis, Jonas, Zhang, Ge, Muglia, Louis J., Jacobsson, Bo
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386882/
https://ncbi.nlm.nih.gov/pubmed/28250013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.038612
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