Prognostic value of loss of heterozygosity and sub-cellular localization of SMAD4 varies with tumor stage in colorectal cancer

BACKGROUND: Although loss of heterozygosity (LOH) at chromosome location 18q21 and decreased expression of SMAD4 in invasive colorectal cancers (CRCs) correlate with poor patient survival, the prognostic value of LOH at 18q21 and sub-cellular localization of SMAD4 have not been evaluated in relation...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jia, Xu, Shanmugam, Chandrakumar, Paluri, Ravi K., Jhala, Nirag C., Behring, Michael P., Katkoori, Venkat R., Sugandha, Shajan P., Bae, Sejong, Samuel, Temesgen, Manne, Upender
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386755/
https://ncbi.nlm.nih.gov/pubmed/28423626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15560
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