Cabozantinib targets bone microenvironment modulating human osteoclast and osteoblast functions

Cabozantinib, a c-MET and vascular endothelial growth factor receptor 2 inhibitor, demonstrated to prolong progression free survival and improve skeletal disease-related endpoints in castration-resistant prostate cancer and in metastatic renal carcinoma. Our purpose is to investigate the direct effe...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Fioramonti, Marco, Santini, Daniele, Iuliani, Michele, Ribelli, Giulia, Manca, Paolo, Papapietro, Nicola, Spiezia, Filippo, Vincenzi, Bruno, Denaro, Vincenzo, Russo, Antonio, Tonini, Giuseppe, Pantano, Francesco
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386748/
https://ncbi.nlm.nih.gov/pubmed/28223547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15390
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