Prognostic impact of immune microenvironment in laryngeal and pharyngeal squamous cell carcinoma: Immune cell subtypes, immuno-suppressive pathways and clinicopathologic characteristics

BACKGROUND: Immune system affects prognosis of various malignancies. Anti-immune pathways like PD-L1 and CTLA4 are used by the tumor to overcome immune system and they serve as immunotherapy targets. The immune microenvironment of head-and-neck squamous cell carcinoma (SCCHN) has not been sufficient...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Karpathiou, Georgia, Casteillo, Francois, Giroult, Jean-Baptiste, Forest, Fabien, Fournel, Pierre, Monaya, Alessandra, Froudarakis, Marios, Dumollard, Jean Marc, Prades, Jean Michel, Peoc'h, Michel
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386686/
https://ncbi.nlm.nih.gov/pubmed/28038471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14242
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