High OCT4A levels drive tumorigenicity and metastatic potential of medulloblastoma cells

Medulloblastoma is a highly aggressive pediatric brain tumor, in which sporadic expression of the pluripotency factor OCT4 has been recently correlated with poor patient survival. However the contribution of specific OCT4 isoforms to tumor aggressiveness is still poorly understood. Here, we report t...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Gonçalves da Silva, Patrícia Benites, Teixeira dos Santos, Márcia Cristina, Rodini, Carolina Oliveira, Kaid, Carolini, Leite Pereira, Márcia Cristina, Furukawa, Gabriela, Gimenes da Cruz, Daniel Sanzio, Goldfeder, Mauricio Barbugiani, Reily Rocha, Clarissa Ribeiro, Rosenberg, Carla, Okamoto, Oswaldo Keith
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386677/
https://ncbi.nlm.nih.gov/pubmed/28186969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15163
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