Parvalbumin Interneurons Modulate Striatal Output and Enhance Performance during Associative Learning

The prevailing view is that striatal parvalbumin (PV)-positive interneurons primarily function to downregulate medium spiny projection neuron (MSN) activity via monosynaptic inhibitory signaling. Here, by combining in vivo neural recordings and optogenetics, we unexpectedly find that both suppressin...

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Gepubliceerd in:Neuron
Hoofdauteurs: Lee, Kwang, Holley, Sandra M., Shobe, Justin L., Chong, Natalie C., Cepeda, Carlos, Levine, Michael S., Masmanidis, Sotiris C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386608/
https://ncbi.nlm.nih.gov/pubmed/28334608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.02.033
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