Bidirectional transcription of Linc00441 and RB1 via H3K27 modification-dependent way promotes hepatocellular carcinoma

The retinoblastoma gene (RB1), a known tumor-suppressor gene (TSG), was decreased in multiple cancers including hepatocellular carcinoma (HCC). Here we focused on the bidirectional transcripted long noncoding RNA (Linc00441) with neighbor gene RB1 to investigate whether Linc00441 is involved in the...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Tang, Junwei, Xie, Yu, Xu, Xiaoliang, Yin, Yin, Jiang, Runqiu, Deng, Lei, Tan, Zhongming, Gangarapu, Venkatanarayana, Tang, Jinhai, Sun, Beicheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386573/
https://ncbi.nlm.nih.gov/pubmed/28300839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.81
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