Mechanical compression induces VEGFA overexpression in breast cancer via DNMT3A-dependent miR-9 downregulation

Tumor growth generates mechanical compression, which may trigger mechanotransduction in cancer and stromal cells and promote tumor progression. However, very little is known about how compression stimulates signal transduction and contributes to tumor progression. In the present study, we demonstrat...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Kim, Baek Gil, Gao, Ming-Qing, Kang, Suki, Choi, Yoon Pyo, Lee, Joo Hyun, Kim, Ji Eun, Han, Hyun Ho, Mun, Seong Gyeong, Cho, Nam Hoon
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386566/
https://ncbi.nlm.nih.gov/pubmed/28252641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.73
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