CARMA2sh and ULK2 control pathogen-associated molecular patterns recognition in human keratinocytes: psoriasis-linked CARMA2sh mutants escape ULK2 censorship

The molecular complexes formed by specific members of the family of CARMA proteins, the CARD domain-containing adapter molecule BCL10 and MALT1 (CBM complex) represent a central hub in regulating activation of the pleiotropic transcription factor NF-κB. Recently, missense mutations in CARMA2sh have...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Scudiero, Ivan, Mazzone, Pellegrino, D'Andrea, Luca E, Ferravante, Angela, Zotti, Tiziana, Telesio, Gianluca, De Rubis, Gabriele, Reale, Carla, Pizzulo, Maddalena, Muralitharan, Shanmugakonar, Vito, Pasquale, Stilo, Romania
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386493/
https://ncbi.nlm.nih.gov/pubmed/28230860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.51
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