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Oncogenic role of rab escort protein 1 through EGFR and STAT3 pathway

Rab escort protein-1 (REP1) is linked to choroideremia (CHM), an X-linked degenerative disorder caused by mutations of the gene encoding REP1 (CHM). REP1 mutant zebrafish showed excessive cell death throughout the body, including the eyes, indicating that REP1 is critical for cell survival, a hallma...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yun, Un-Jung, Sung, Jee Young, Park, Seog-Yun, Ye, Sang-Kyu, Shim, Jaegal, Lee, Jae-Seon, Hibi, Masahiko, Bae, Young-Ki, Kim, Yong-Nyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386492/
https://ncbi.nlm.nih.gov/pubmed/28230863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.50
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