Starvation at birth impairs germ cell cyst breakdown and increases autophagy and apoptosis in mouse oocytes

The female reproductive lifespan is largely determined by the size of primordial follicle pool, which is established following germ cell cyst breakdown around birth. Almost two-third of oocytes are lost during germ cell cysts breakdown, following autophagic and apoptosis mechanisms. To investigate a...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Wang, Yong-Yong, Sun, Yuan-Chao, Sun, Xiao-Feng, Cheng, Shun-Feng, Li, Bo, Zhang, Xi-Feng, De Felici, Massimo, Shen, Wei
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386484/
https://ncbi.nlm.nih.gov/pubmed/28182014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.3
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