Starvation at birth impairs germ cell cyst breakdown and increases autophagy and apoptosis in mouse oocytes

The female reproductive lifespan is largely determined by the size of primordial follicle pool, which is established following germ cell cyst breakdown around birth. Almost two-third of oocytes are lost during germ cell cysts breakdown, following autophagic and apoptosis mechanisms. To investigate a...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Yong-Yong, Sun, Yuan-Chao, Sun, Xiao-Feng, Cheng, Shun-Feng, Li, Bo, Zhang, Xi-Feng, De Felici, Massimo, Shen, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386484/
https://ncbi.nlm.nih.gov/pubmed/28182014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.3
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