Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene

Neuropathic pain-like joint symptoms (NP) are seen in a proportion of individuals diagnosed with osteoarthritis (OA) and post total joint replacement (TJR). In this study, we performed a genome-wide association study (GWAS) using NP as defined by the painDETECT questionnaire (score >12 indicating...

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Vydáno v:Eur J Hum Genet
Hlavní autoři: Warner, Sophie C, van Meurs, Joyce BJ, Schiphof, Dieuwke, Bierma-Zeinstra, Sita M, Hofman, Albert, Uitterlinden, Andre G, Richardson, Helen, Jenkins, Wendy, Doherty, Michael, Valdes, Ana M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386416/
https://ncbi.nlm.nih.gov/pubmed/28051079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.196
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