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The TAZ–miR-224–SMAD4 axis promotes tumorigenesis in osteosarcoma

Transcriptional co-activator with PDZ-binding motif (TAZ) is a downstream effector of the Hippo signaling pathway that participates in tumorigenesis. The aim of this study was to identify the miRNA counterpart for TAZ and elucidate the mechanism underlying the tumorigenic effect of TAZ. We demonstra...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ma, Jianjun, Huang, Kangmao, Ma, Yan, Zhou, Menglu, Fan, Shunwu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386375/
https://ncbi.nlm.nih.gov/pubmed/28055015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.468
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