REP1 inhibits FOXO3-mediated apoptosis to promote cancer cell survival

Rab escort protein 1 (REP1) is a component of Rab geranyl-geranyl transferase 2 complex. Mutations in REP1 cause a disease called choroideremia (CHM), which is an X-linked eye disease. Although it is postulated that REP1 has functions in cell survival or death of various tissues in addition to the e...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Song, Kwon-Ho, Woo, Seon Rang, Chung, Joon-Yong, Lee, Hyo-Jung, Oh, Se Jin, Hong, Soon-Oh, Shim, Jaegal, Kim, Yong Nyun, Rho, Seung Bae, Hong, Seung-Mo, Cho, Hanbyoul, Hibi, Masahiko, Bae, Dong-Jun, Kim, Sang-Yeob, Kim, Min Gyu, Kim, Tae Woo, Bae, Young-Ki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386371/
https://ncbi.nlm.nih.gov/pubmed/28055019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.462
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