Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration

Histone deacetylases (HDACs), especially HDAC1, 2, 3 and 4, are abundantly expressed and over-activated in prostate cancer that is correlated with the poor prognosis. Thus, inhibition of HDAC activity has emerged as a potential alternative option for prostate cancer therapy. Chromopeptide A is a dep...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Sun, Jing-ya, Wang, Ji-dong, Wang, Xin, Liu, Hong-chun, Zhang, Min-min, Liu, Yu-Chih, Zhang, Chen-hua, Su, Yi, Shen, Yan-yan, Guo, Yue-wei, Shen, Ai-jun, Geng, Mei-yu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386309/
https://ncbi.nlm.nih.gov/pubmed/28112184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.139
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