Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase

BACKGROUND: Schistosomiasis, a severe disease caused by parasites of the genus Schistosoma, is prevalent in 74 countries, affecting more than 250 million people, particularly children. We have previously shown that the Schistosoma mansoni gut-derived cysteine peptidase, cathepsin B1 (SmCB1), adminis...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Negl Trop Dis
Main Authors: Tallima, Hatem, Dvořák, Jan, Kareem, Sahira, Abou El Dahab, Marwa, Abdel Aziz, Nada, Dalton, John Pius, El Ridi, Rashika
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386297/
https://ncbi.nlm.nih.gov/pubmed/28346516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005443
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