Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase

BACKGROUND: Schistosomiasis, a severe disease caused by parasites of the genus Schistosoma, is prevalent in 74 countries, affecting more than 250 million people, particularly children. We have previously shown that the Schistosoma mansoni gut-derived cysteine peptidase, cathepsin B1 (SmCB1), adminis...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Tallima, Hatem, Dvořák, Jan, Kareem, Sahira, Abou El Dahab, Marwa, Abdel Aziz, Nada, Dalton, John Pius, El Ridi, Rashika
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386297/
https://ncbi.nlm.nih.gov/pubmed/28346516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005443
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