Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells

Pancreatic β cell dysfunction and reduction due to glucose toxicity play a crucial role in the development of type 2 diabetes mellitus (T2DM). Irisin, a novel exercise-induced myokine, reduces obesity, improves insulin resistance and lowers blood glucose by promoting the browning of white adipose ti...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Liu, Shiwei, Du, Fang, Li, Xin, Wang, Mingming, Duan, Ruixue, Zhang, Jiaxin, Wu, Yaru, Zhang, Qi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386279/
https://ncbi.nlm.nih.gov/pubmed/28394923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175498
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