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Toll-like receptor 4 contributes to the inhibitory effect of morphine on colonic motility in vitro and in vivo
Opioids rank among the most potent analgesic drugs but gastrointestinal side effects, especially constipation, limit their therapeutic utility. The adverse effects of opioids have been attributed to stimulation of opioid receptors, but emerging evidence suggests that opioids interact with the innate...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5386182/ https://ncbi.nlm.nih.gov/pubmed/25962524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09499 |
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