Human monoclonal antibodies to the human immunodeficiency virus type 1 (HIV-1) transmembrane glycoprotein gp41 enhance HIV-1 infection in vitro.

Three of 16 human monoclonal antibodies (hu-mAbs) enhanced human immunodeficiency virus type 1 (HIV-1) infection of MT-2 target cells by means of a mechanism that is dependent on complement. Enhanced infections are characterized by an increase in cytopathic effects and antigen synthesis as well as a...

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Autores principales: Robinson, W E, Kawamura, T, Gorny, M K, Lake, D, Xu, J Y, Matsumoto, Y, Sugano, T, Masuho, Y, Mitchell, W M, Hersh, E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC53860/
https://ncbi.nlm.nih.gov/pubmed/2326277
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