Mass Spectroscopic Characterization of the Coronavirus Infectious Bronchitis Virus Nucleoprotein and Elucidation of the Role of Phosphorylation in RNA Binding by Using Surface Plasmon Resonance

Phosphorylation of the coronavirus nucleoprotein (N protein) has been predicted to play a role in RNA binding. To investigate this hypothesis, we examined the kinetics of RNA binding between nonphosphorylated and phosphorylated infectious bronchitis virus N protein with nonviral and viral RNA by sur...

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Detalhes bibliográficos
Main Authors: Chen, Hongying, Gill, Andrew, Dove, Brian K., Emmett, Stevan R., Kemp, C. Fred, Ritchie, Mark A., Dee, Michael, Hiscox, Julian A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538594/
https://ncbi.nlm.nih.gov/pubmed/15613344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1164-1179.2005
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