Mass Spectroscopic Characterization of the Coronavirus Infectious Bronchitis Virus Nucleoprotein and Elucidation of the Role of Phosphorylation in RNA Binding by Using Surface Plasmon Resonance

Phosphorylation of the coronavirus nucleoprotein (N protein) has been predicted to play a role in RNA binding. To investigate this hypothesis, we examined the kinetics of RNA binding between nonphosphorylated and phosphorylated infectious bronchitis virus N protein with nonviral and viral RNA by sur...

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Autors principals: Chen, Hongying, Gill, Andrew, Dove, Brian K., Emmett, Stevan R., Kemp, C. Fred, Ritchie, Mark A., Dee, Michael, Hiscox, Julian A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC538594/
https://ncbi.nlm.nih.gov/pubmed/15613344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1164-1179.2005
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