A rationally-designed, general strategy for membrane orientation of photoinduced electron transfer-based voltage-sensitive dyes

Voltage imaging with fluorescent dyes offers promise for interrogating the complex roles of membrane potential in coordinating the activity of neurons in the brain. Yet, low sensitivity often limits the broad applicability of optical voltage indicators. In this paper, we use molecular dynamics (MD)...

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Bibliographic Details
Published in:ACS Chem Biol
Main Authors: Kulkarni, Rishikesh U., Yin, Hang, Pourmandi, Narges, James, Feroz, Adil, Maroof M., Schaffer, David V., Wang, Yi, Miller, Evan W.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385922/
https://ncbi.nlm.nih.gov/pubmed/28004909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00981
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