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Chimeric opioid peptides: tools for identifying opioid receptor types.

We synthesized several chimeric peptides in which the N-terminal nine residues of dynorphin-32, a peptide selective for the kappa opioid receptor, were replaced by opioid peptides selective for other opioid receptor types. Each chimeric peptide retained the high affinity and type selectivity charact...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Xie, G X, Miyajima, A, Yokota, T, Arai, K, Goldstein, A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53859/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2158105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.8.3180
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