Quercetin Inhibits Pulmonary Arterial Endothelial Cell Transdifferentiation Possibly by Akt and Erk1/2 Pathways

This study aimed to investigate the effects and mechanisms of quercetin on pulmonary arterial endothelial cell (PAEC) transdifferentiation into smooth muscle-like cells. TGF-β1-induced PAEC transdifferentiation models were applied to evaluate the pharmacological actions of quercetin. PAEC proliferat...

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Res Int
Hauptverfasser: Huang, Shian, Zhu, Xiulong, Huang, Wenjun, He, Yuan, Pang, Lingpin, Lan, Xiaozhong, Shui, Xiaorong, Chen, Yanfang, Chen, Can, Lei, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385898/
https://ncbi.nlm.nih.gov/pubmed/28428963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6147294
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