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Terminal Differentiation into Plasma Cells Initiates the Replicative Cycle of Epstein-Barr Virus In Vivo

In this paper we demonstrate that the cells which initiate replication of Epstein-Barr virus (EBV) in the tonsils of healthy carriers are plasma cells (CD38(hi), CD10(−), CD19(+), CD20(lo), surface immunoglobulin negative, and cytoplasmic immunoglobulin positive). We further conclude that differenti...

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Main Authors: Laichalk, Lauri L., Thorley-Lawson, David A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC538585/
https://ncbi.nlm.nih.gov/pubmed/15613356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1296-1307.2005
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