A Complex Zinc Finger Controls the Enzymatic Activities of Nidovirus Helicases

Nidoviruses (Coronaviridae, Arteriviridae, and Roniviridae) encode a nonstructural protein, called nsp10 in arteriviruses and nsp13 in coronaviruses, that is comprised of a C-terminal superfamily 1 helicase domain and an N-terminal, putative zinc-binding domain (ZBD). Previously, mutations in the eq...

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Autors principals: Seybert, Anja, Posthuma, Clara C., van Dinten, Leonie C., Snijder, Eric J., Gorbalenya, Alexander E., Ziebuhr, John
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC538568/
https://ncbi.nlm.nih.gov/pubmed/15613297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.696-704.2005
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