Opening of Size-Selective Pores in Endosomes during Human Rhinovirus Serotype 2 In Vivo Uncoating Monitored by Single-Organelle Flow Analysis

The effect of virus uncoating on endosome integrity during the early steps in viral infection was investigated. Using fluid-phase uptake of 10- and 70-kDa dextrans labeled with a pH-dependent fluorophore (fluorescein isothiocyanate [FITC]) and a pH-independent fluorophore (cyanine 5 [Cy5]), we deter...

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Detalhes bibliográficos
Main Authors: Brabec, Marianne, Schober, Daniela, Wagner, Ernst, Bayer, Nora, Murphy, Robert F., Blaas, Dieter, Fuchs, Renate
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538566/
https://ncbi.nlm.nih.gov/pubmed/15613329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1008-1016.2005
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