Control of tissue size and development by a regulatory element in the yorkie 3’UTR

Regulation of the Hippo pathway via phosphorylation of Yorkie (Yki), the Drosophila homolog of human Yes-associated protein 1, is conserved from Drosophila to humans. Overexpression of a non-phosphorylatable form of Yki induces severe overgrowth in adult fly eyes. Here, we show that yki mRNA associa...

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Detalles Bibliográficos
Publicado en:Am J Cancer Res
Main Authors: Umegawachi, Takanari, Yoshida, Hideki, Koshida, Hiromu, Yamada, Momoko, Ohkawa, Yasuyuki, Sato, Tetsuya, Suyama, Mikita, Krause, Henry M, Yamaguchi, Masamitsu
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385651/
https://ncbi.nlm.nih.gov/pubmed/28401020
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