CpG Methylation Directly Regulates Transcriptional Activity of the Human Endogenous Retrovirus Family HERV-K(HML-2)

A significant proportion of the human genome consists of stably inherited retroviral sequences. Most human endogenous retroviruses (HERVs) became defective over time. The HERV-K(HML-2) family is exceptional because of its coding capacity and the possible involvement in germ cell tumor (GCT) developm...

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Bibliographic Details
Main Authors: Lavie, Laurence, Kitova, Milena, Maldener, Esther, Meese, Eckart, Mayer, Jens
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Recombination and Evolution
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC538560/
https://ncbi.nlm.nih.gov/pubmed/15613316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.876-883.2005
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