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Loss of Polycomb Group Protein Pcgf1 Severely Compromises Proper Differentiation of Embryonic Stem Cells

The Polycomb repressive complex 1 (PRC1) is essential for fate decisions of embryonic stem (ES) cells. Emerging evidence suggests that six major variants of PRC1 complex, defined by the mutually exclusive presence of Pcgf subunit, regulate distinct biological processes, yet very little is known abou...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Yan, Yun, Zhao, Wukui, Huang, Yikai, Tong, Huan, Xia, Yin, Jiang, Qing, Qin, Jinzhong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385539/
https://ncbi.nlm.nih.gov/pubmed/28393894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46276
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