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Deletion of Penton RGD Motifs Affects the Efficiency of both the Internalization and the Endosome Escape of Viral Particles Containing Adenovirus Serotype 5 or 35 Fiber Knobs

Adenovirus (Ad) vectors are widely used for gene delivery in vitro and in vivo. A solid understanding of the biology of this virus is imperative for the development of novel, effective, and safe vectors. For the group C adenovirus serotypes 2 and 5 that use CAR as a primary attachment receptor, it i...

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Autors principals: Shayakhmetov, Dmitry M., Eberly, Andrea M., Li, Zong-Yi, Lieber, André
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC538548/
https://ncbi.nlm.nih.gov/pubmed/15613334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1053-1061.2005
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