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Roles of Carboxyl-Terminal and Farnesylated Residues in the Functions of the Large Hepatitis Delta Antigen

The large hepatitis delta antigen (HDAg-L) mediates hepatitis delta virus (HDV) assembly and inhibits HDV RNA replication. Farnesylation of the cysteine residue within the HDAg-L carboxyl terminus is required for both functions. Here, HDAg-L proteins from different HDV genotypes and genotype chimeri...

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Bibliografische gegevens
Hoofdauteurs: O'Malley, Brendan, Lazinski, David W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538544/
https://ncbi.nlm.nih.gov/pubmed/15613342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1142-1153.2005
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