Cullin 4A is associated with epithelial to mesenchymal transition and poor prognosis in perihilar cholangiocarcinoma

AIM: To explore the functional role of cullin 4A (CUL4A), a core subunit of E3 ubiquitin ligase, in perihilar cholangiocarcinoma (PHCC). METHODS: The expression of CUL4A in PHCC cell lines was evaluated by Western blot and quantitative reverse transcription-polymerase chain reaction. Immunohistochem...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: Zhang, Tong-Jun, Xue, Dong, Zhang, Cheng-De, Zhang, Ze-Dong, Liu, Qing-Ran, Wang, Jian-Qiang
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2017
Subjects:
Basic Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385398/
https://ncbi.nlm.nih.gov/pubmed/28428711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i13.2318
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