Interleukin 6 regulates metallothionein gene expression and zinc metabolism in hepatocyte monolayer cultures.

Attention has focused on the cytokine interleukin 6 (IL-6) as a major mediator of acute-phase protein synthesis in hepatocytes in response to infection and tissue injury. We have evaluated the effects of IL-6 and IL-1 alpha as well as extracellular zinc and glucocorticoid hormone on metallothionein...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Schroeder, J J, Cousins, R J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53849/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2326272/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.8.3137
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