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In Vivo pH Mapping of Injured Lungs Using Hyperpolarized [1-13C] Pyruvate

PURPOSE: To optimize the production of hyperpolarized (13)C-bicarbonate from the decarboxylation of hyperpolarized [1-(13)C]pyruvate and use it to image pH in the lungs and heart of rats with acute lung injury. METHODS: Two forms of catalysis are compared calorimetrically to maximize the reaction ra...

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Bibliographic Details
Published in:Magn Reson Med
Main Authors: Drachman, Nicholas, Kadlecek, Stephen, Pourfathi, Mehrdad, Xin, Yi, Profka, Harilla, Rizi, Rahim
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384877/
https://ncbi.nlm.nih.gov/pubmed/27714832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.26473
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