A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides

Mucorales are a group of basal fungi that includes the casual agents of the human emerging disease mucormycosis. Recent studies revealed that these pathogens activate an RNAi-based pathway to rapidly generate drug-resistant epimutant strains when exposed to stressful compounds such as the antifungal...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Calo, Silvia, Nicolás, Francisco E., Lee, Soo Chan, Vila, Ana, Cervantes, Maria, Torres-Martinez, Santiago, Ruiz-Vazquez, Rosa M., Cardenas, Maria E., Heitman, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384783/
https://ncbi.nlm.nih.gov/pubmed/28339467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006686
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