Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and catalytic efficiency

NAD(+) has emerged as a crucial element in both bioenergetic and signaling pathways since it acts as a key regulator of cellular and organismal homeostasis. Among the enzymes involved in its recycling, nicotinamide mononucleotide (NMN) deamidase is one of the key players in the bacterial pyridine nu...

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Veröffentlicht in:PLoS One
Hauptverfasser: Martínez-Moñino, Ana Belén, Zapata-Pérez, Rubén, García-Saura, Antonio Ginés, Gil-Ortiz, Fernando, Pérez-Gilabert, Manuela, Sánchez-Ferrer, Álvaro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384747/
https://ncbi.nlm.nih.gov/pubmed/28388636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174759
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