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IgG Fc variant cross-reactivity between human and rhesus macaque FcγRs

Non-human primate (NHP) studies are often an essential component of antibody development efforts before human trials. Because the efficacy or toxicity of candidate antibodies may depend on their interactions with Fcγ receptors (FcγR) and their resulting ability to induce FcγR-mediated effector funct...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Boesch, Austin W., Miles, Adam R., Chan, Ying N., Osei-Owusu, Nana Y., Ackerman, Margaret E.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384711/
https://ncbi.nlm.nih.gov/pubmed/28055295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1274845
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